I'm currently taking a course at uni called "Transnational Smuggling" and I want to see 007 bust an international human trafficking operation that smuggles young people from the UAE into the United Kingdom. It's the most sordid illicit trade and the second most lucrative (after drugs) in the world and very relevant in the 21st century. It would fall under MI6's jurisdiction but the operation would need a really unique and vile leader for the Double O Section to be involved.
That, I think, would be too much like TAKEN. After all Liam Nesson's daughter was bound for Dubai in that film. Or maybe Abu Dhabi. The point is that TAKEN got a lot of acclaim for being a tight little thriller, and in the face of the "It's James Bourne!" criticism of the Age of Craig, the last think we need is accusations of Bond apeing TAKEN, even if it is in novel format and not film.
An idea that was floated on the Other Forum was that it is not actually smoke, but some kind of liquid polymer. I could see a plot revolving around a villain planning to dump masses of a liquid polymer into the port of Dubai; when the polymer meets water, it starts to thicken, amking it virtually impossible for ships to enter the port, crippling the economy of Dubai. It would open up a really interesting possibility: having a villain who shares a similar belief to Bond - both could treat Dubai with open disdain. We've never really had a villain who had a relationship like that with Bond. The closest we've come is Scaramanga, who believed he and Bond were similar until Bond rejected him, and Graves, who was always intended as a dark parody of Bond. I think it would be interesting to see Bond realise he and the villain looked at Dubai the same way, and then search to find more they had in common. Generally, I'd like to see a villain that Bond would actually, genuinely like if they were on opposite sides.