I'm probably being overly-optimistic here, but I do think that there might be a viewer market for faithful adaptations of Fleming's novels that are set in their proper time period. However, that market wouldn't extend to the "major motion picture" market. But something more along the lines of a TV mini-series might just work. Shows like Boardwalk Empire, Downton Abbey, and of course Mad Men have shown that there's not only an interest in 'period pieces' but also that these 'period pieces' can be successfully filmed in such a way as to make the audience believe they are looking through a time-machine.
However, I think there are a few hurdles to cross before such an endeavor could be successful:
(1) The obvious conflict that would result between this and the current version of movie-007. In order to promote such a project, the creators would certainly have to rely on such promotion lines" like "For the first time ever, see 007 as Fleming intended" or something like that. Having two or three different incarnations of Sherlock Holmes being presented to the pubic is one thing, but I think having more than one 007 might prove to Eon to be "counterproductive." Then there's the whole problem of "reintroducing" the view to "real" Goldfinger, Live and Let Die, You Only Live Twice, etc.
(2) As exciting as they are to read, I don't think that the pacing of Fleming's novels would hold the modern-day viewers' attention very long. No matter how interested/curious viewers would be to see "the real 007", I think they would bring with them certain expectations from their previous experiences of watching the movie-007.
(3) Along with Fleming's pacing, quite a few pages of his novels are devoted to 'setting the scene' and making the reader feel as if they are actually in Jamaica, Japan, coast of France, etc... and not mention the pages he devotes to 007's meals, etc. Now don't get me wrong - those pages are some of the best parts of his works. However, I can't see how there's way to bring that Fleming "magic" to film or TV. So from the starting gate, we're looking at eliminating some of most important aspects of his works. And, without that added "third person" narrative, what would be left would be a film/TV-version of the newspaper comic strips.
(4) Speaking of the "third person" narrative - in order for the viewer to 'connect' with this endeavor's Bond, it would almost certainly have to rely on a "first person" narrative, with Bond speaking directly to the viewer to offer insights into his thoughts and motivations for his actions. Aside from it being one step further away from the Fleming novels (with Bond suddenly talking to the viewer directly), this technique could easily fall into the category of a bad parody of "film noir."
(4)