Under these circumstances it seems a reasonably safe bet that adult Bond will see another continuation, all the more so as there already have been hints coming from IFP's direction. The questions that remain to be answered would be:
When will another continuation be announced?
Will it be connected to some form of 'celebration' (for example '60 years of literary Bond in 2013' or '50 years of EON Bond in 2012')?
Will the setting again be 'period' or 'present'?
Will it once more be a one-off?
Will it see a similar amount of publicity?
From IFP's moves so far I think we can gain the following intelligence regarding their policy.
Every fiction project, from Charlie Higson's Young Bond to Samantha Weinberg's Moneypenny Diaries and of course DMC, has seen a considerable amount of time from the initial announcement to the final presentation to the public. This may mean that the announcement in these cases came only shortly after the contracts were signed and before the respective first installments were finished or authors even started work (apart perhaps from a rough overview or first draft).
Every fiction project has had its limits clearly defined from the start: 5 Young Bond volumes, 3 Moneypenny Diaries, 1 Centennary Celebration.
As a rule IFP seems to avoid hasty decisions and to observe the market for its products closely to avoid cheapening its brand by flooding it. The long intervals between the outings may also indicate a considerable amount of editorial work on the respective books, although this may not be the case with every book or even be necessary.
With regard to the questions above it seems reasonable to expect an announcement of a new adult Bond novel within the next 2 to 3 years. A connection with '60 years of literary Bond' would seem natural, setting a publishing date somewhere in 2013. Any connection with EON's series would seem unlikely to me. The setting of the next continuation would most likely again be 'period', considering the success of the 'period' YB and MD and also taking into account that nobody seemed to object to DMC's late 60's setting. The one-off question isn't answered so easily as IFP would probably like to take one author on board for a longer stint. I daresay nonetheless that we'll again see another one-off. This would dovetail with IFP's policy to 'make it special'. While a similar amount of publicity for IFP's next Bond outing is really almost impossible, it seems obvious that all the media-generated hype around DMC has paid handsomely and every penny spent on all these publicity stunts has earned at least five cousins. It would be most surprising if IFP wouldn't keep in very close touch with the media to announce and promote any new installment of Bond; be that Young Bond, Young Bond II, Moneypenny or adult Bond.
This last point is actually the most difficult to handle. While Ian Fleming's 100th birthday has made for a spectacular year stuffed with events, new releases and re-releases, it's hardly possible to repeat this massive media coverage. One way though to create and spur media interest in a new Bond novel would be to carefully chose and contract an author whose name would again be major headline fodder. Sebastian Faulks was a surprise to most readers and perhaps even to most insiders. Getting a name with a similar standing would be the most urgent and difficult task. My personal choice would be (in no particular order):
William Boyd, Stephen Fry or Ken Follett. Follett, while not a very surprising choice, perhaps even a little bit unimaginative, would also mean that a new Bond would certainly do well in Germany as his works are generally to be found in the top three of all bestseller lists for at least 6 months. DMC went next to unnoticed on this market with an amazone rank of 10160. Follett would see to that. Both Boyd and Fry are not as popular in Germany as Follett but also do have a firm fanbase that would give any of their books a comfortable start and would guarantee that their book would be noticed by professional reviewers.
Or get Jim and conquer not just GB, USA and Europe but the world!