Destroy All Humans 2 has a lot of references: it starts by having Crypto (the main protagonist) say, "D'you expect me to beg, human?", to which the KGB agent replies, "No, little Furon, I expect you to die!". Soon after this, there is a mission entitled, "The Alien Who Probed Me".
When you get to Albion (London), you occasionally encounter Secret Agents, who will shoot at you with a Golden Gun, and then you meet Reginald Ponsonby-Smythe, "at your service. And Her Majesty's. Though, in Her case, the Service is Secret". This M16 (Majestic Command, 16th Sector) Agent has a machine-gun umbrella, straight out of Q-Branch.
Soon after this, in "From Russia With Guns", Natalya (the friendly neighbourhood KGB Officer) tells you that you have to meet her KGB contact, Agent Sergei, a reference to Anya's man in TSWLM.
Later, once you escape from Ponsonby, the British Secret Service is out in force, complete with a veritable army of Aston Martin DB5's, with registration plate "006". The very next mission is called "On Natalya's Secret Service".
Once you get the Takoshima (the city formerly known as Tokyo), you encounter many ninjas, the spiritual leader of whom is called Dr. Go, a friendly, if bloody irritating little man who looks just like YOLT's Blofeld, but with an eyepatch. He gives you the passcode to get into the KGB base inside the volcano, Mt. Seiyuki: "Eye Love Ewe". Then, in "You Only Live 137 times" (a reference to the fact that you are Cryptosporidium-137, in theory - I'm always up to about Crypto-180 or something), you get into the base, and escape through a cave that leads to the sea.
Also, the title screen has a girl's silhouette run on, point a gun, and run off.
Edited by 007½, 26 April 2009 - 02:18 PM.